1. Evidence-based Drug Therapy

Evidence based migraine prophylactic drug therapy.

Prophylactic drug therapy is a major component of overall migraine management. However, because we do not know how currently used prophylactic drugs exert their beneficial effects in migraine, their use is based primarily on clinical trials. In general, prophylactic drugs are indicated when patients have three or more attacks a month and symptomatic medication use alone is not satisfactory. The...

Stepped Care: an Evidence-based Approach to Drug Therapy

Editors’ Note: This month we continue the feature STEPped Care: An Evidence-Based Approach to Drug Therapy. These articles are designed to provide concise answers to the drug therapy questions that family physicians encounter in their daily practice. The format of the feature will follow the mnemonic STEP: safety (an analysis of adverse effects that patients and providers care about), tolerabil...

STEPPED CARE: AN EvIDENCE-BASED APPROACH TO DRUG THERAPY

Editors' Note: This month we continue the new featureSTEPped Care: An Evidence-BasedApproach to Drug Therapy. These articles are designed to provide concise answers to the drog therapy questions that family physicians encounter in their daily practice. The format of the feature will follow the mnemonic STEP: safety (an analysis of adverse effects that patients and providers care about), tolerab...

HIV-1 antiretroviral drug therapy.

The most significant advance in the medical management of HIV-1 infection has been the treatment of patients with antiviral drugs, which can suppress HIV-1 replication to undetectable levels. The discovery of HIV-1 as the causative agent of AIDS together with an ever-increasing understanding of the virus replication cycle have been instrumental in this effort by providing researchers with the k...

Evidence Based Physical Therapy